Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03251)
Xenobiotics Name
Enterocin AS-48
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Klebsiella variicola [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Salmonella enterica [2]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [2]
Beta-lactamase (blaB) DME Info Enterobacter cloacae [3]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [2]
Beta-lactamase (blaB) DME Info Shigella sonnei [2]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [2]
Cytidine deaminase (cdd) DME Info Escherichia coli [1]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [3]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [3]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [3]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [3]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [2]
Unclear metabolic mechanism (DME-unclear) DME Info Salmonella enterica [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
Beta-galactosidase (bgaB) DME Info Enterobacter cloacae [3]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [2]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Salmonella enterica [2]
Nitroreductase (NTR) DME Info Enterobacter cloacae [3]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Salmonella enterica [2]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas fluorescens [2]
Retro-nitroreductase (rNR) DME Info Enterobacter cloacae [3]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
References
1 Bacteriocin AS-48, a microbial cyclic polypeptide structurally and functionally related to mammalian NK-lysin. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11221-6.
2 Bactericidal and bacteriolytic action of peptide antibiotic AS-48 against gram-positive and gram-negative bacteria and other organisms. Res Microbiol. 1989 Jan;140(1):57-68.
3 Structure of bacteriocin AS-48: from soluble state to membrane bound state. J Mol Biol. 2003 Nov 28;334(3):541-9.

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