General Information of Drug-Metabolizing Enzyme (DME ID: DME1243)
DME Name NADPH-dependent nitroreductase (nfrA1), Bacillus subtilis DME Info
UniProt ID
NFRA1_BACSU
EC Number    EC: 1.5.1.38     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
CH-NH donor oxidoreductase
NAD/NADP acceptor oxidoreductase
EC: 1.5.1.38
Lineage    Species: Bacillus subtilis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Bacillaceae
Genus: Bacillus
Species: Bacillus subtilis
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:    400 Xenobiotics
                              40S ribosomal protein S30 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02013   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation 40S ribosomal protein S30 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [1]
                              A. dichotoma defensin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02102   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation A. dichotoma defensin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [2]
                              Agelaia-mastoparan Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02147   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Agelaia-mastoparan inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 237 ug/ml) [3], [4]
                              AI-hemocidins 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02151   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation AI-hemocidins 4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 69.55 microM) [5]
                              Amphipathic peptide StCT1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02200   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Amphipathic peptide StCT1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 100 ug/ml) [6]
                              Amphipathic peptide StCT2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02201   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Amphipathic peptide StCT2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 ug/ml) [7]
                              Amphiphatic peptide VmCT1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02202   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Amphiphatic peptide VmCT1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20 microM) [8]
                              Amphiphatic peptide VmCT2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02203   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Amphiphatic peptide VmCT2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20 microM) [8]
                              Androctonin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02224   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Androctonin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [9]
                              Andropin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02226   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Andropin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 17 microM) [10]
                              Antibacterial napin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02237   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antibacterial napin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 236 microM) [11]
                              Antibacterial peptide enbocin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02241   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antibacterial peptide enbocin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [12]
                              Antibacterial protein PR-39 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02248   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antibacterial protein PR-39 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 15 microM) [13], [14]
                              Anticancerous peptide Cr-ACP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02249   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Anticancerous peptide Cr-ACP1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 microM) [15]
                              Antimicrobial peptide Ar-AMP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02278   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide Ar-AMP inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [16]
                              Antimicrobial peptide Cn-AMP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02261   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide Cn-AMP1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 76 ug/ml) [17]
                              Antimicrobial peptide Cn-AMP2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02268   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide Cn-AMP2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 150 ug/ml) [17]
                              Antimicrobial peptide Cn-AMP3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02271   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide Cn-AMP3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 257 ug/ml) [17]
                              Antimicrobial peptide GP-19 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02282   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide GP-19 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [18]
                              Antimicrobial peptide HP(2-20) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02283   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide HP(2-20) inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.13 ug/ml) [19]
                              Antimicrobial peptide ISAMP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02288   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide ISAMP inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.3 ug/ml) [20], [21]
                              Antimicrobial peptide lumbricin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02289   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide lumbricin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12 ug/ml) [22]
                              Antimicrobial protein Ah-AMP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02146   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial protein Ah-AMP1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [23]
                              Antimicrobial protein AN5-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02298   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial protein AN5-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 32 ug/ml) [24]
                              Antimicrobial protein BL-A60 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02300   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial protein BL-A60 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 5 microM) [25]
                              Arasin-likeSp Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02316   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Arasin-likeSp inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25-12.5 microM) [26]
                              Arthropod Im-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03627   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Arthropod Im-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.8-1.6 microM) [27]
                              ASABF-alpha Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02320   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ASABF-alpha inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [28], [29]
                              Astacidin 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02332   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Astacidin 2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.95 ug/ml) [30]
                              Bactenecin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02735   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC < 2 ug/ml) [31]
                              Bacteriocin HJ50 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02476   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bacteriocin HJ50 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [32], [33]
                              Bacteriocin lacticin Q Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03771   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bacteriocin lacticin Q inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [34]
                              Basic peptide AMP1 IB-AMP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03623   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Basic peptide AMP1 IB-AMP1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [35], [36]
                              Basic peptide AMP4 IB-AMP4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03624   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Basic peptide AMP4 IB-AMP4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [35], [36]
                              Big defensin RPD-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02452   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Big defensin RPD-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 76800 ug/ml) [37]
                              Biologically active peptide BmKn2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04541   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Biologically active peptide BmKn2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 5 ug/ml) [38]
                              BmKn2 derivative Kn2-7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03709   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation BmKn2 derivative Kn2-7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25 ug/ml) [39]
                              Bradykinin-potentiating BmK3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02491   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bradykinin-potentiating BmK3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 24.4 microM) [40], [41]
                              Brevinin-1LT1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02532   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-1LT1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25 microM) [42]
                              Brevinin-2-RN1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02630   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-2-RN1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 ug/ml) [43]
                              Brevinin-2-RN2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02631   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-2-RN2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 ug/ml) [43]
                              Brevinin-2GHa Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02588   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-2GHa inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 64 ug/ml) [44]
                              Brevinin-2GHb Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02589   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-2GHb inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 64 ug/ml) [44]
                              Brevinin-2GHc Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02590   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-2GHc inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 64 ug/ml) [44]
                              Brevinin-2ISa Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02595   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-2ISa inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 microM) [45]
                              Brevinin-2ISb Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02596   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Brevinin-2ISb inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 microM) [45]
                              Buforin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02649   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Buforin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4 ug/ml) [46], [47]
                              Buforin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02650   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Buforin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [46], [47]
                              C. ternatea-antimicrobial peptide Ct-AMP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02966   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation C. ternatea-antimicrobial peptide Ct-AMP1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [48]
                              Cathelicidin-AL Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02741   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cathelicidin-AL inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 100 ug/ml) [49]
                              Cathelicidin-BF Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02743   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cathelicidin-BF inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 9.4 ug/ml) [50], [51]
                              cathelicidin-BF15 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02744   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation cathelicidin-BF15 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 75 ug/ml) [50]
                              Cecropin-A(1-7)-melittin(1-8) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02756   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-7)-melittin(1-8) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.4 microM) [52]
                              Cecropin-A(1-7)-melittin(2-9) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02757   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-7)-melittin(2-9) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.5 microM) [52], [53]
                              Cecropin-A(1-7)-melittin(3-10) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02758   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-7)-melittin(3-10) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3 microM) [52]
                              Cecropin-A(1-7)-melittin(4-11) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02759   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-7)-melittin(4-11) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.6 microM) [52], [54]
                              Cecropin-A(1-7)-melittin(5-12) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02760   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-7)-melittin(5-12) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.3 microM) [52]
                              Cecropin-A(1-7)-melittin(6-13) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02761   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-7)-melittin(6-13) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1 microM) [52]
                              Cecropin-A(1-8)-Magainin-2(1-12) hybrid P18 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04430   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-8)-Magainin-2(1-12) hybrid P18 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55], [56]
                              Cecropin-A(1-8)-melittin(1-10) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02762   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-8)-melittin(1-10) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.3 microM) [52]
                              Cecropin-A(1-8)-melittin(1-12) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02763   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-8)-melittin(1-12) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.3 microM) [52]
                              Cecropin-A(1-8)-melittin(1-13) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02764   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-8)-melittin(1-13) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [52]
                              Cecropin-A(1-8)-melittin(1-18) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02765   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-A(1-8)-melittin(1-18) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.4 microM) [52]
                              Cecropin-B(1-7)-melittin(4-11) hybrid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02767   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-B(1-7)-melittin(4-11) hybrid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [54]
                              Cecropin-D Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02771   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-D inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 81 microM) [57]
                              Ceratotoxin-C Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02802   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ceratotoxin-C inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 5.9 microM) [58]
                              Chain of Platelet basic TC-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03606   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Chain of Platelet basic TC-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [59], [60]
                              Chain of Platelet basic TC-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03607   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Chain of Platelet basic TC-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [59], [60]
                              Charybdotoxin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02821   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Charybdotoxin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [61]
                              Chrysophsin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02839   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Chrysophsin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.25 microM) [62]
                              Chrysophsin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02841   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Chrysophsin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.25 microM) [62]
                              Chrysophsin-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02842   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Chrysophsin-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.25 microM) [62]
                              CP-P derivative K11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03678   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP-P derivative K11 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [63]
                              Crab GRPSp peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03510   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Crab GRPSp peptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 50 microM) [26]
                              Cryptonin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02962   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cryptonin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.12 ug/ml) [64]
                              D-amino acid substitution of K9L8W Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03060   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation D-amino acid substitution of K9L8W inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1 microM) [65]
                              Decoralin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03089   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Decoralin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 40 microM) [66]
                              Defensin Cll-dlp Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03112   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin Cll-dlp inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 50 ug/ml) [67]
                              Defensin Ns-D1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03103   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin Ns-D1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [68]
                              Defensin Ns-D2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03105   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin Ns-D2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [68]
                              Defensin varisin A1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03101   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin varisin A1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [69], [70]
                              Defensin-like protein brazzein Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03124   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin-like protein brazzein inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [61], [71]
                              Defensin-like protein Dm-AMP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03120   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin-like protein Dm-AMP1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [72]
                              Defensin-like protein fabatin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03121   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin-like protein fabatin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [73]
                              Defensin-like protein fabatin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03123   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin-like protein fabatin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [73]
                              Dolabellanin B2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03215   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dolabellanin B2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.5 ug/ml) [74]
                              Dominulin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03216   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dominulin-A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [75]
                              Dominulin-B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03217   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dominulin-B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [75]
                              Drosophila cecropin-A1/A2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03225   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Drosophila cecropin-A1/A2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 16 microM) [76]
                              Drosophila cecropin-B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03223   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Drosophila cecropin-B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.2 microM) [77], [78]
                              Dybowskin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03233   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dybowskin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [79]
                              Dybowskin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03235   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dybowskin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 ug/ml) [79]
                              Dybowskin-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03237   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dybowskin-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 60 ug/ml) [79]
                              Dybowskin-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03238   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dybowskin-4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25 ug/ml) [79]
                              Dybowskin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03239   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dybowskin-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [79]
                              Dybowskin-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03240   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dybowskin-6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [79]
                              Enterocin 96 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03250   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Enterocin 96 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [80]
                              Enterocin B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03252   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Enterocin B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 44.5 microM) [81], [82]
                              Enterocin EJ97 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03254   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Enterocin EJ97 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12 ug/ml) [83]
                              Enterocin RJ-11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03258   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Enterocin RJ-11 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [84]
                              Enterocin X beta Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03260   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Enterocin X beta inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.25 microM) [85]
                              Ericin S Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03270   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ericin S inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [86]
                              Esculentin-1ISa Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03281   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Esculentin-1ISa inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 microM) [45]
                              Esculentin-1ISb Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03282   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Esculentin-1ISb inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 microM) [45]
                              Esculentin-2ISa Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03306   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Esculentin-2ISa inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.3 microM) [45]
                              Eumenine mastoparan-AF Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03362   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Eumenine mastoparan-AF inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 40 ug/ml) [87]
                              Eumenine mastoparan-EF Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03363   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Eumenine mastoparan-EF inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 microM) [88]
                              Eumenine mastoparan-ER Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03364   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Eumenine mastoparan-ER inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 microM) [88]
                              Eumenitin Er-12 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03366   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Eumenitin Er-12 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 60 microM) [89], [90]
                              Eumenitin F Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03367   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Eumenitin F inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 microM) [88]
                              Eumenitin R Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03368   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Eumenitin R inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 7.5 microM) [88]
                              Gaegurin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03436   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [91]
                              Gaegurin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03437   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 ug/ml) [91]
                              Gaegurin-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03438   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 ug/ml) [91]
                              Gaegurin-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03439   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 ug/ml) [92]
                              Gaegurin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03440   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 ug/ml) [91]
                              Gaegurin-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03441   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 ug/ml) [91]
                              Gaegurin-RN1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03442   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-RN1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4.69 ug/ml) [93]
                              Gaegurin-RN4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03443   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-RN4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.34 ug/ml) [93]
                              Gaegurin-RN5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03444   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-RN5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4.69 ug/ml) [93]
                              GAPDH-related antimicrobial YFGAP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05308   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation GAPDH-related antimicrobial YFGAP inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 ug/ml) [94]
                              Geobacillin I Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03478   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Geobacillin I inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [95]
                              Geobacillin II Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03479   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Geobacillin II inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [95]
                              GGN4 analogue peptide D16W Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03052   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation GGN4 analogue peptide D16W inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.5 ug/ml) [96]
                              Gramicidin S Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03503   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gramicidin S inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.6 ug/ml) [97]
                              Gramicidin [Scr2]-GS analogue Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03501   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gramicidin [Scr2]-GS analogue inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.3 ug/ml) [97]
                              Grammistin Gs A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03504   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Grammistin Gs A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 ug/ml) [98]
                              Grammistin Gs B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03505   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Grammistin Gs B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25 ug/ml) [98]
                              Grammistin Gs C Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03506   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Grammistin Gs C inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25 ug/ml) [98]
                              Guentherin AMP-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03512   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Guentherin AMP-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 64 ug/ml) [44]
                              Heligoland antimicrobial peptide A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04762   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Heligoland antimicrobial peptide A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.1 microM) [99]
                              Hepcidin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03542   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hepcidin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6 microM) [100], [101]
                              Hepcidin AS-hepc6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03544   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hepcidin AS-hepc6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [102]
                              Heteroscorpine-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03549   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Heteroscorpine-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [103]
                              Hinnavin I Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03561   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hinnavin I inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [104]
                              Histone H2A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03566   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Histone H2A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.6-1.2 microM) [105]
                              Histone-derived oncorhyncin III Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04397   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Histone-derived oncorhyncin III inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.25-0.5 microM) [106]
                              HP(2-20) analogue Anal 1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02207   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 ug/ml) [19]
                              HP(2-20) analogue Anal 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02208   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 ug/ml) [19]
                              HP(2-20) analogue Anal 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02209   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 ug/ml) [19]
                              HP(2-20) analogue Anal 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02210   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25 ug/ml) [19]
                              HP(2-20) analogue Anal 5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02211   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.13 ug/ml) [19]
                              HP(2-20) analogue Anal 6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02212   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 ug/ml) [19]
                              HP(2-20) analogue Anal 7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02213   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 ug/ml) [19]
                              Hylin-a1 Hy-a1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03616   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hylin-a1 Hy-a1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8 microM) [107]
                              Immobilized peptide E07LKK Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03633   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E07LKK inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E10KKL Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03630   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E10KKL inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E12LLK Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03631   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E12LLK inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E14KKL Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03632   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E14KKL inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E14LKK/H14LKK Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03634   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E14LKK/H14LKK inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E16LKL Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03635   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E16LKL inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E17HSA magainin 2 deletion Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03636   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E17HSA magainin 2 deletion inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E17KGG Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03637   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E17KGG inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E18KGG Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03638   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E18KGG inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptide E23GIG magainin 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03639   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptide E23GIG magainin 2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immobilized peptige E16KGL/H16KGL Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03640   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immobilized peptige E16KGL/H16KGL inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [108]
                              Immune protein P9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02769   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immune protein P9 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 18 microM) [109]
                              Insect cecropin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02768   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect cecropin-A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [109]
                              Insect cecropin-B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02770   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect cecropin-B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 17 microM) [57], [110]
                              Insect cecropin-D Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02772   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect cecropin-D inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [109], [111]
                              Insect defensin A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03116   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect defensin A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 40 microM) [112]
                              Insect defensin B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03117   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect defensin B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20-40 microM) [112]
                              Insect peptide C Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04542   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect peptide C inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [113]
                              Insect PP102 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04711   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect PP102 peptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 microM) [114]
                              Insect PP113 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04712   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect PP113 peptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 23.3 microM) [114]
                              Insect PP13 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04713   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect PP13 peptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 13.3 microM) [114]
                              Ixodes ricinus defensin def1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03664   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ixodes ricinus defensin def1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.5 microM) [115]
                              Ixodes ricinus defensin def2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03665   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ixodes ricinus defensin def2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.75 microM) [115]
                              Jellein-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03672   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Jellein-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 ug/ml) [116]
                              Jellein-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03673   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Jellein-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 ug/ml) [116]
                              L-amino-acid oxidase Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03793   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L-amino-acid oxidase inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 32 microM) [117]
                              L5K5Wn model peptide L5K5W1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03746   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              L5K5Wn model peptide L5K5W10 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03747   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W10 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1 ug/ml) [118]
                              L5K5Wn model peptide L5K5W11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03748   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W11 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              L5K5Wn model peptide L5K5W2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03749   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              L5K5Wn model peptide L5K5W3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03750   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              L5K5Wn model peptide L5K5W4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03751   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              L5K5Wn model peptide L5K5W5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03752   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              L5K5Wn model peptide L5K5W7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03754   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              L5K5Wn model peptide L5K5W8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03755   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W8 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4 ug/ml) [118]
                              L5K5Wn model peptide L5K5W9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03756   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W9 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 ug/ml) [118]
                              Lantibiotic lichenicidin VK21 A1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03804   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lantibiotic lichenicidin VK21 A1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [119]
                              Lantibiotic lichenicidin VK21 A2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03805   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lantibiotic lichenicidin VK21 A2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [119]
                              Lasioglossin III derivative LL-III Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03947   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin III derivative LL-III inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.5 microM) [120]
                              Lasioglossin LL-I derivative 1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03933   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-I derivative 1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.3 microM) [120]
                              Lasioglossin LL-I derivative 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03934   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-I derivative 2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.6 microM) [120]
                              Lasioglossin LL-I derivative 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03935   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-I derivative 3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [120]
                              Lasioglossin LL-I derivative 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03936   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-I derivative 4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.9 microM) [120]
                              Lasioglossin LL-II derivative 1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03937   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-II derivative 1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [120]
                              Lasioglossin LL-II derivative 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03938   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-II derivative 2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [120]
                              Lasioglossin LL-II derivative 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03939   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-II derivative 3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [120]
                              Lasioglossin LL-II derivative 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03940   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-II derivative 4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [120]
                              Lasioglossin LL-III derivative 1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03941   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-III derivative 1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [120]
                              Lasioglossin LL-III derivative 10 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03942   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-III derivative 10 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 100 microM) [120]
                              Lasioglossin LL-III derivative 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03943   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-III derivative 2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.6 microM) [120]
                              Lasioglossin LL-III derivative 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03944   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-III derivative 3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.7 microM) [120]
                              Lasioglossin LL-III derivative 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03945   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-III derivative 4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.8 microM) [120]
                              Lasioglossin LL-III derivative 7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03948   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-III derivative 7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4.7 microM) [120]
                              Lasioglossin LL-III derivative 8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03949   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lasioglossin LL-III derivative 8 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 40 microM) [120]
                              Laterosporulin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03810   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Laterosporulin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [121]
                              LL-37(17-29) peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03928   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LL-37(17-29) peptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 16 microM) [122], [123]
                              LlKmWn model peptide L4K2W4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03737   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L4K2W4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 ug/ml) [124]
                              LlKmWn model peptide L4K3W4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03739   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L4K3W4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [124]
                              LlKmWn model peptide L4K3W5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03740   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L4K3W5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [124]
                              LlKmWn model peptide L5K3W5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03744   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L5K3W5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 ug/ml) [124]
                              LlKmWn model peptide L5K5W6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03753   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L5K5W6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.3 ug/ml) [124]
                              LlKmWn model peptide L6K4W6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03759   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L6K4W6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.6 ug/ml) [124]
                              LlKmWn model peptide L7K3W6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03761   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L7K3W6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.6 ug/ml) [124]
                              LlKmWn model peptide L7K5W7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03762   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L7K5W7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.1 ug/ml) [124]
                              LlKmWn model peptide L8K4W7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03764   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LlKmWn model peptide L8K4W7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.3 ug/ml) [124]
                              Lumbrican Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03971   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lumbrican inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [22]
                              Lumbricin I(6-34) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03972   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lumbricin I(6-34) inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8 ug/ml) [22]
                              Lunatusin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03973   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lunatusin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [125]
                              M-lycotoxin-Ls3a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04121   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-lycotoxin-Ls3a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.6-3.2 microM) [126]
                              M-lycotoxin-Ls3b Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04122   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-lycotoxin-Ls3b inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.57-3.14 microM) [126]
                              M-theraphotoxin-Gr1a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04142   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-theraphotoxin-Gr1a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.5 microM) [127]
                              M-zodatoxin-Lt1a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04177   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt1a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.0 microM) [128], [129]
                              M-zodatoxin-Lt2a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04178   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt2a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.4 microM) [128], [130]
                              M-zodatoxin-Lt3a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04179   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt3a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.2 microM) [128]
                              M-zodatoxin-Lt3b Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04180   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt3b inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.9 microM) [128]
                              M-zodatoxin-Lt4a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04181   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt4a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.1 microM) [128]
                              M-zodatoxin-Lt4b Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04182   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt4b inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.1 microM) [128]
                              M-zodatoxin-Lt5a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04183   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt5a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.6 microM) [128]
                              M-zodatoxin-Lt8a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04184   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt8a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.9 microM) [131]
                              M-zodatoxin-Lt8c Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04185   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt8c inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [131]
                              Mastoparan MP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03996   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mastoparan MP inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 9 microM) [132]
                              Mastoparan MP-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04000   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mastoparan MP-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4 ug/ml) [133]
                              Mastoparan PDD-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03997   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mastoparan PDD-A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 11.8 microM) [132]
                              Mastoparan PDD-B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03998   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mastoparan PDD-B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 70 microM) [132]
                              Mastoparan PMM Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03999   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mastoparan PMM inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 7.3 microM) [132]
                              Melectin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04055   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Melectin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.8 microM) [134]
                              Melittin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04057   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Melittin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.2 microM) [135]
                              Moricin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04128   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Moricin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.19 microM) [136], [137]
                              MP analog MP-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04138   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation MP analog MP-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 15 microM) [132]
                              MP analog MP-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04139   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation MP analog MP-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 microM) [132]
                              MP analog MP-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04140   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation MP analog MP-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 35 microM) [132]
                              MP analog MP-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04141   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation MP analog MP-6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 40 microM) [132]
                              Mucroporin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04149   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mucroporin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [138], [139]
                              Myticusin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04168   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Myticusin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.2-2.5 microM) [140]
                              Naegleriapore A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04233   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Naegleriapore A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [141]
                              Naegleriapore B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04234   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Naegleriapore B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [141]
                              Napin-like polypeptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04235   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Napin-like polypeptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [142]
                              Nematode ABF-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02115   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nematode ABF-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [143]
                              Nigroain-C2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04277   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigroain-C2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 110.00 ug/ml) [93]
                              Nigroain-D3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04278   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigroain-D3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 55 ug/ml) [93]
                              Nigroain-K1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04280   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigroain-K1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 21.88 ug/ml) [93]
                              Nigroain-K2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04281   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigroain-K2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 9.38 ug/ml) [93]
                              Nigrocin-2ISa Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04298   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigrocin-2ISa inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 microM) [45]
                              Nigrocin-2ISb Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04299   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigrocin-2ISb inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 microM) [45]
                              Nigrocin-OG4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04307   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigrocin-OG4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 100 ug/ml) [144]
                              Nigrocin-OG5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04308   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigrocin-OG5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 37.50 ug/ml) [144]
                              Nigrosin-OG13 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04312   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigrosin-OG13 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 18.75 ug/ml) [144]
                              Nigrosin-OG21 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04313   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nigrosin-OG21 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 18.75 ug/ml) [144]
                              Non-disulfide-bridged peptide BmKb1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04540   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Non-disulfide-bridged peptide BmKb1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 48.8 ug/ml) [38], [145]
                              Odorranain-B1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04355   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-B1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.85 ug/ml) [144]
                              Odorranain-C1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04356   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-C1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 16.42 ug/ml) [144]
                              Odorranain-D1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04357   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-D1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8.16 ug/ml) [144]
                              Odorranain-E1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04358   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-E1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4.68 ug/ml) [144]
                              Odorranain-F1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04359   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-F1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8.40 ug/ml) [144]
                              Odorranain-G1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04365   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-G1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 37.5 ug/ml) [144]
                              Odorranain-H1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04366   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-H1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 5.90 ug/ml) [144]
                              Odorranain-J1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04367   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-J1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 35.60 ug/ml) [144]
                              Odorranain-K1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04370   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-K1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.10 ug/ml) [144]
                              Odorranain-M1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04371   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-M1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 75 ug/ml) [144]
                              Odorranain-P1a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04374   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-P1a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.75 ug/ml) [144]
                              Odorranain-P2a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04375   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-P2a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 ug/ml) [144]
                              Odorranain-S1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04377   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-S1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 85.00 ug/ml) [144]
                              Odorranain-T1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04378   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-T1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 17.50 ug/ml) [144]
                              Odorranain-U1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04379   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-U1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 9.37 ug/ml) [144]
                              Odorranain-V1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04380   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-V1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 18.00 ug/ml) [144]
                              Odorranain-W1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04381   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-W1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.30 ug/ml) [144]
                              Oncorhyncin III Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04396   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Oncorhyncin III inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.25-0.5 microM) [106]
                              Opistoporin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04399   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Opistoporin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 microM) [146]
                              Oxyopinin-1 M-oxotoxin-Ot1a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04137   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Oxyopinin-1 M-oxotoxin-Ot1a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [147], [148]
                              Oxyopinin-4a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04421   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Oxyopinin-4a inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.5 microM) [149]
                              Oyster cgUbiquitin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02807   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Oyster cgUbiquitin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.4 ug/mL) [150]
                              P18 analog N-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04206   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analog N-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04214   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analog N-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04216   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analog N-3L Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04218   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-3L inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analog N-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04219   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analog N-4L Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04220   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-4L inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analog N-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04221   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analog N-5L Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04222   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analog N-5L inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analogue C-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02663   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analogue C-10 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02664   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-10 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              P18 analogue C-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02672   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              P18 analogue C-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02673   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78-1.56 microM) [55]
                              P18 analogue C-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02674   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              P18 analogue C-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02676   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analogue C-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02677   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.78 microM) [55]
                              P18 analogue C-7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02679   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              P18 analogue C-8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02680   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-8 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              P18 analogue C-9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02683   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue C-9 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              P18 analogue L9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01823   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue L9 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              P18 analogue S9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01825   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation P18 analogue S9 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.56 microM) [55]
                              Palustrin-2ISa Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04448   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Palustrin-2ISa inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 microM) [45]
                              Palustrin-2ISc Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04455   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Palustrin-2ISc inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 microM) [151]
                              Palustrin-OG1 derivative OG2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04383   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Palustrin-OG1 derivative OG2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 128 ug/ml) [152]
                              Pandinin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04461   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pandinin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 5.2 microM) [153], [154]
                              Pandinin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04462   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pandinin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4.8 microM) [148]
                              Parabutoporin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04471   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Parabutoporin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.3 microM) [155]
                              PDD-A analog PDD-A-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04484   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 45 microM) [132]
                              PDD-A analog PDD-A-10 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04485   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-10 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 microM) [132]
                              PDD-A analog PDD-A-11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04486   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-11 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 15 microM) [132]
                              PDD-A analog PDD-A-12 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04487   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-12 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20 microM) [132]
                              PDD-A analog PDD-A-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04488   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 5 microM) [132]
                              PDD-A analog PDD-A-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04489   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8.5 microM) [132]
                              PDD-A analog PDD-A-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04490   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 17.5 microM) [132]
                              PDD-A analog PDD-A-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04491   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 17 microM) [132]
                              PDD-A analog PDD-A-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04492   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 40 microM) [132]
                              PDD-A analog PDD-A-7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04493   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 87.5 microM) [132]
                              PDD-A analog PDD-A-8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04494   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-8 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 100 microM) [132]
                              PDD-A analog PDD-A-9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04495   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-A-9 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 22.5 microM) [132]
                              PDD-A analog PDD-B-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04496   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-B-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 microM) [132]
                              PDD-A analog PDD-B-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04497   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-B-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 17.5 microM) [132]
                              PDD-A analog PDD-B-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04498   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-B-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 22.5 microM) [132]
                              PDD-A analog PDD-B-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04499   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-B-4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 15.5 microM) [132]
                              PDD-A analog PDD-B-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04500   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PDD-A analog PDD-B-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 100 microM) [132]
                              Pep-1 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04525   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pep-1 peptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8.0 microM) [156]
                              Pep-1 peptide derivative Pep-1-K Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04526   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pep-1 peptide derivative Pep-1-K inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.0 microM) [156]
                              Pilosulin 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04604   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pilosulin 3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC < 50 microM) [157]
                              Pilosulin 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04605   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pilosulin 4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC < 50 microM) [157]
                              Plant defensin Pn-AMP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04678   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plant defensin Pn-AMP1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [158]
                              Plant defensin Pn-AMP2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04679   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plant defensin Pn-AMP2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [158]
                              Plant JCpep7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03671   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plant JCpep7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 24 ug/ml) [159]
                              Plantazolicin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04624   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plantazolicin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [160]
                              Pleurain-B1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04632   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-B1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.1 ug/ml) [161]
                              Pleurain-C1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04633   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-C1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.1 ug/ml) [161]
                              Pleurain-D4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04634   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-D4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [161]
                              Pleurain-G1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04636   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-G1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 100 ug/ml) [161]
                              Pleurain-J1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04637   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-J1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [161]
                              Pleurain-R1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04639   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-R1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 100 ug/ml) [161]
                              Pleurocidin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04640   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.1-2.2 microM) [162]
                              PMM analog PMM-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04664   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 27.2 microM) [132]
                              PMM analog PMM-10 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04665   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-10 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 35 microM) [132]
                              PMM analog PMM-11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04666   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-11 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 100 microM) [132]
                              PMM analog PMM-12 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04667   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-12 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 microM) [132]
                              PMM analog PMM-13 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04668   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-13 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 60 microM) [132]
                              PMM analog PMM-14 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04669   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-14 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 microM) [132]
                              PMM analog PMM-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04670   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 46 microM) [132]
                              PMM analog PMM-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04671   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 125 microM) [132]
                              PMM analog PMM-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04672   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 75 microM) [132]
                              PMM analog PMM-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04673   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 100 microM) [132]
                              PMM analog PMM-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04674   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-6 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 70 microM) [132]
                              PMM analog PMM-7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04675   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-7 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 100 microM) [132]
                              PMM analog PMM-8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04676   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-8 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 100 microM) [132]
                              PMM analog PMM-9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04677   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PMM analog PMM-9 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 100 microM) [132]
                              Polybia chemotactic peptide polybia-CP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04681   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Polybia chemotactic peptide polybia-CP inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 15 ug/ml) [133]
                              Ponericin G1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04695   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin G1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [163]
                              Ponericin G4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04697   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin G4 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [163]
                              Pore-forming peptide ameobapore A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04707   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pore-forming peptide ameobapore A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 27 microM) [164]
                              Pro-rich PP30 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04714   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pro-rich PP30 peptide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 16.7 microM) [165]
                              Protonectin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04737   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Protonectin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 3.1 ug/ml) [3], [4]
                              PYLa/PGLa A chain PGLa-H Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04551   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PYLa/PGLa A chain PGLa-H inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 14.4 ug/ml) [166], [167]
                              Ranacyclin-B-AL1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04790   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ranacyclin-B-AL1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 26 microM) [168]
                              Ranacyclin-B-RL1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04793   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ranacyclin-B-RL1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 46.2 microM) [168]
                              Rugosin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04865   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rugosin-A inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 12.5 ug/ml) [169]
                              Rugosin-B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04866   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rugosin-B inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25 ug/ml) [169]
                              Rugosin-RN1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04868   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rugosin-RN1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 9.38 ug/ml) [93]
                              Rugosin-RN3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04869   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rugosin-RN3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 18.75 ug/ml) [93]
                              Rugosin-RN5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04870   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rugosin-RN5 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 18.75 ug/ml) [93]
                              SAMP H1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04901   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SAMP H1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2 microM) [170]
                              Sapecin defensin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04904   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Sapecin defensin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20.0 ug/ml) [171], [172]
                              Sarcotoxin-1D Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04909   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Sarcotoxin-1D inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [171]
                              Scorpine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04917   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Scorpine inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.0 microM) [173]
                              Seabream beta defensin saBD Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04892   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Seabream beta defensin saBD inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [174]
                              Single AA substitution D16F-N23 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03051   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Single AA substitution D16F-N23 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 ug/ml) [96]
                              Single AA substitution D16W-N23 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03053   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Single AA substitution D16W-N23 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 ug/ml) [96]
                              SMAP-29 derivative A19 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01810   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 derivative A19 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.0 microM) [175]
                              SMAP-29 derivative K2,7,13 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01817   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 derivative K2,7,13 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4.0 microM) [175]
                              SMAP-29 derivative K22,25,27 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01818   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 derivative K22,25,27 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 4.0 microM) [175]
                              SMAP-29 peptide derivative(1-17) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04956   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 peptide derivative(1-17) inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8.0 microM) [175]
                              Spheniscin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04971   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Spheniscin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.8-1.5 microM) [176], [177]
                              Stomoxyn Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04995   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Stomoxyn inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 6.25-12.5 microM) [178], [179]
                              Temporin-GH Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05089   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Temporin-GH inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC > 64 ug/ml) [44]
                              Temporin-LT1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05092   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Temporin-LT1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 microM) [42]
                              Temporin-LT2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05093   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Temporin-LT2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 microM) [42]
                              Temporin-LTa Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05094   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Temporin-LTa inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 10 ug/ml) [180]
                              Temporin-LTb Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05095   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Temporin-LTb inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 25 ug/ml) [180]
                              Temporin-LTc Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05096   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Temporin-LTc inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 50 ug/ml) [180]
                              Thanatin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05120   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thanatin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.5-5 microM) [181], [182]
                              Thanatin truncated isoform G18C(1-18) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03431   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thanatin truncated isoform G18C(1-18) inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 5-10 microM) [181]
                              Thanatin truncated isoform G20R(1-20) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03435   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thanatin truncated isoform G20R(1-20) inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20-40 microM) [181]
                              Thanatin truncated isoform K18M(4-21) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03681   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thanatin truncated isoform K18M(4-21) inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20-40 microM) [181]
                              Thanatin truncated isoform V16M(6-21) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05220   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thanatin truncated isoform V16M(6-21) inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20-40 microM) [181]
                              Thiocillin GE37468 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05129   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thiocillin GE37468 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 0.047 ug/ml) [183]
                              Thuricin-17 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05138   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thuricin-17 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [184]
                              Thuricin-S Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05139   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thuricin-S inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [185]
                              Tigerinin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05144   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tigerinin-1 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 ug/ml) [186]
                              Tigerinin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05145   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tigerinin-2 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 20 ug/ml) [186]
                              Tigerinin-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05146   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tigerinin-3 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 30 ug/ml) [186]
                              Tricyclic peptide MS-271 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05169   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tricyclic peptide MS-271 inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [187]
                              Tritrpticin derivative TPA Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05161   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tritrpticin derivative TPA inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 16 ug/ml) [188]
                              Tritrpticin derivative TPG Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05162   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tritrpticin derivative TPG inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 16 ug/ml) [188]
                              Tritrpticin peptide derivative TWF Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05193   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tritrpticin peptide derivative TWF inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 8 ug/ml) [188]
                              Type 1 invertebrate defensin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03100   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Type 1 invertebrate defensin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [189]
                              V681 peptide derivative S11AD Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04886   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation V681 peptide derivative S11AD inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 1.3 ug/ml) [190]
                              V681 peptide derivative S11G Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04880   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation V681 peptide derivative S11G inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.0 ug/ml) [190]
                              V681 peptide derivative V13G Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05212   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation V681 peptide derivative V13G inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis (MIC = 2.0 ug/ml) [190]
      Health or Environmental Toxicant(s)
                  Health Hazard/Toxicant Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Mucochloric acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04148   XEOTIC Info Gene Form Protein
                                 Classification Health Hazard
                                 DME Modulation Mucochloric acid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [191]
      Natural Product(s), Extract(s) or Medicine(s)
                  Bacterial Extract Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Bacillus licheniformis SP1 culture supernatant Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02990   XEOTIC Info Gene Form Protein
                                 Classification Bacterial Extract
                                 DME Modulation Bacillus licheniformis SP1 culture supernatant inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [192]
                  Natural Product Click to Show/Hide the Full List of Xenobiotics:        2 Xenobiotics
                              Anthranilate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02235   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Anthranilate inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [193]
                              Penicillic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04518   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Penicillic acid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [194]
                  Sponge Extract Click to Show/Hide the Full List of Xenobiotics:        5 Xenobiotics
                              Amphimedon chloros sponge extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04975   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Amphimedon chloros sponge extract inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [195]
                              Crella cyathophora sponge extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04976   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Crella cyathophora sponge extract inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [195]
                              Diacarnus erythraenus sponge extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04977   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Diacarnus erythraenus sponge extract inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [195]
                              Pione vastifica sponge extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04978   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Pione vastifica sponge extract inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [195]
                              Sarcotragus sp sponge extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04979   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Sarcotragus sp sponge extract inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [195]
      Pharmaceutical Agent(s)
                  Approved/Marketed Drug Click to Show/Hide the Full List of Xenobiotics:        8 Xenobiotics
                              Amlodipine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00338   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Amlodipine inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                              Amoxicillin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00246   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Amoxicillin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                              Ampicillin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00096   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Ampicillin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                              Cefixime Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02780   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Cefixime inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                              Cephalexin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02801   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Cephalexin inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                              Enalapril Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00356   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Enalapril inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                              Esomeprazole Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00070   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Esomeprazole inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                              Glipizide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00044   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Glipizide inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [196]
                  Drug in Phase 1 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              L-tryptophan Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03968   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1
                                 DME Modulation L-tryptophan inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [193]
                  Investigative Agent Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Norspermidine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04331   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Norspermidine inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [197]
      Other Chemical Compound(s) or Element(s)
                  Chemical Compound Click to Show/Hide the Full List of Xenobiotics:        2 Xenobiotics
                              3,4-Dichloro-2-(1,3-dichloropropan-2-yloxy)-2H-furan-5-one Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01972   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation 3,4-Dichloro-2-(1,3-dichloropropan-2-yloxy)-2H-furan-5-one inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [191]
                              Mucobromic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04147   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Mucobromic acid inhibits the drug-metabolizing activity of NADPH-dependent nitroreductase (nfrA1) from Bacillus subtilis [191]
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11 A napin-like polypeptide from dwarf Chinese white cabbage seeds with translation-inhibitory, trypsin-inhibitory, and antibacterial activities. Peptides. 2004 Feb;25(2):171-6.
12 Cloning and expression of a novel gene encoding a new antibacterial peptide from silkworm, Bombyx mori. Biochem Biophys Res Commun. 1998 May 19;246(2):388-92.
13 Amino acid sequence of PR-39Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem. 1991 Dec 18;202(3):849-54.
14 Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7085-9.
15 Identification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties. J Cell Biochem. 2012 Jan;113(1):184-93.
16 An antimicrobial peptide Ar-AMP from amaranth (Amaranthus retroflexus L.) seeds. Phytochemistry. 2005 Oct;66(20):2426-31.
17 Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water. Peptides. 2009 Apr;30(4):633-7.
18 Two novel antimicrobial peptides purified from the symbiotic bacteria Xenorhabdus budapestensis NMC-10. Peptides. 2012 Jun;35(2):253-60.
19 Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-14.
20 Exploring the sialome of the tick Ixodes scapularis. J Exp Biol. 2002 Sep;205(Pt 18):2843-64.
21 Purification and characterization of a novel salivary antimicrobial peptide from the tick, Ixodes scapularis. Biochem Biophys Res Commun. 2009 Dec 18;390(3):511-5.
22 Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization. Biochim Biophys Acta. 1998 Oct 22;1408(1):67-76.
23 Specific binding sites for an antifungal plant defensin from Dahlia (Dahlia merckii) on fungal cells are required for antifungal activity. Mol Plant Microbe Interact. 2000 Jan;13(1):54-61.
24 Detection of secreted antimicrobial peptides isolated from cell-free culture supernatant of Paenibacillus alvei AN5. J Ind Microbiol Biotechnol. 2013 Jun;40(6):571-9.
25 Purification and characterization of a novel antimicrobial peptide from Brevibacillus laterosporus strain A60. Peptides. 2012 Feb;33(2):206-11.
26 Two novel antimicrobial peptides, arasin-likeSp and GRPSp, from the mud crab Scylla paramamosain, exhibit the activity against some crustacean pathogenic bacteria. Fish Shellfish Immunol. 2011 Feb;30(2):706-12.
27 A novel amphipathic linear peptide with both insect toxicity and antimicrobial activity from the venom of the scorpion Isometrus maculatus. Biosci Biotechnol Biochem. 2010;74(2):364-9.
28 ASABF, a novel cysteine-rich antibacterial peptide isolated from the nematode Ascaris suumPurification, primary structure, and molecular cloning of cDNA. J Biol Chem. 1996 Nov 29;271(48):30493-8.
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30 Antibacterial peptides in hemocytes and hematopoietic tissue from freshwater crayfish Pacifastacus leniusculus: characterization and expression pattern. Dev Comp Immunol. 2007;31(5):441-55.
31 Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes. Infect Immun. 1999 Aug;67(8):4106-11.
32 Bovicin HJ50, a novel lantibiotic produced by Streptococcus bovis HJ50. Microbiology. 2004 Jan;150(Pt 1):103-108.
33 Characteristics of the bovicin HJ50 gene cluster in Streptococcus bovis HJ50. Microbiology. 2009 Feb;155(Pt 2):584-593.
34 Structural analysis and characterization of lacticin Q, a novel bacteriocin belonging to a new family of unmodified bacteriocins of gram-positive bacteria. Appl Environ Microbiol. 2007 May;73(9):2871-7.
35 A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein. J Biol Chem. 1997 Sep 26;272(39):24480-7.
36 Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1). Biochemistry. 1998 Jan 27;37(4):983-90.
37 Purification of a big defensin from Ruditapes philippinesis and its antibacterial activity. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Dec;35(12):1145-8.
38 Identification and functional characterization of novel scorpion venom peptides with no disulfide bridge from Buthus martensii Karsch. Peptides. 2004 Feb;25(2):143-50.
39 Antibacterial activity and mechanism of a scorpion venom peptide derivative in vitro and in vivo. PLoS One. 2012;7(7):e40135.
40 Cloning and characterization of a novel cDNA sequence encoding the precursor of a novel venom peptide (BmKbpp) related to a bradykinin-potentiating peptide from Chinese scorpion Buthus martensii Karsch. IUBMB Life. 2000 Mar;49(3):207-10.
41 Characterization of BmKbpp, a multifunctional peptide from the Chinese scorpion Mesobuthus martensii Karsch: gaining insight into a new mechanism for the functional diversification of scorpion venom peptides. Peptides. 2012 Jan;33(1):44-51.
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43 Two novel antimicrobial peptides from skin secretions of the frog, Rana nigrovittata. J Pept Sci. 2011 Jan;17(1):68-72.
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150 Purification and antimicrobial function of ubiquitin isolated from the gill of Pacific oyster, Crassostrea gigas. Mol Immunol. 2013 Jan;53(1-2):88-98.
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156 Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1. Biochem Biophys Res Commun. 2006 Oct 20;349(2):769-74.
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