General Information of Xenobiotics (ID: XEO04471)
Xenobiotics Name
Parabutoporin
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Klebsiella variicola [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1]
Cytidine deaminase (cdd) DME Info Escherichia coli [1]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1]
Unclear metabolic mechanism (DME-unclear) DME Info Saccharomyces cerevisiae [1]
Glutamate decarboxylase (gadB) DME Info Listeria monocytogenes [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 3.1 microM [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 3.1 microM [1]
Beta-lactamase (blaB) DME Info MIC = 1.6 microM [1]
Beta-lactamase (blaB) DME Info MIC = 3.1 microM [1]
Beta-lactamase (blaB) DME Info MIC = 1.6 microM [1]
Metallo-beta-lactamase (blaM) DME Info MIC = 1.6 microM [1]
Beta-lactamase (blaB) DME Info MIC = 1.6 microM [1]
Cytidine deaminase (cdd) DME Info MIC = 1.6 microM [1]
Cytidine deaminase (cdd) DME Info MIC = 1.6 microM [1]
Chloramphenicolase (chlR) DME Info MIC = 3.1 microM [1]
Glycoside hydrolase (cscA) DME Info MIC = 3.1 microM [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 3.1 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 3.1 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1.6 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 2 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 6.3 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 3.1 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 3.1 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 6.3 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 1.6 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 3.1 microM [1]
Methylthioribose kinase (mtnK) DME Info MIC = 1.6 microM [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 1.6 microM [1]
Glutamate racemase (MurI) DME Info MIC = 3.1 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 6.3 microM [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 3.1 microM [1]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 6.3 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 3.1 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 3.1 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 1.6 microM [1]
NADH dehydrogenase (nuoE) DME Info MIC = 3.1 microM [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 6.3 microM [1]
Glutamate racemase (MurI) DME Info MIC = 6.3 microM [1]
Tyramine oxidase (tynA) DME Info MIC = 3.1 microM [1]
Beta-glucuronidase (uidA) DME Info MIC = 3.1 microM [1]
Glutamate racemase (MurI) DME Info MIC = 6.3 microM [1]
General stress protein 14 (ywrO) DME Info MIC = 6.3 microM [1]
References
1 Parabutoporin--an antibiotic peptide from scorpion venom--can both induce activation and inhibition of granulocyte cell functions. Peptides. 2004 Jul;25(7):1079-84.
2 Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. Eur J Biochem. 2002 Oct;269(19):4799-810.

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