General Information of Xenobiotics (ID: XEO03753)
Xenobiotics Name
LlKmWn model peptide L5K5W6
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Klebsiella variicola [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1]
Cytidine deaminase (cdd) DME Info Escherichia coli [1]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 12.5 ug/ml [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 12.5 ug/ml [1]
Beta-lactamase (blaB) DME Info MIC = 6.3 ug/ml [1]
Beta-lactamase (blaB) DME Info MIC = 12.5 ug/ml [1]
Beta-lactamase (blaB) DME Info MIC = 6.3 ug/ml [1]
Metallo-beta-lactamase (blaM) DME Info MIC = 6.3 ug/ml [1]
Beta-lactamase (blaB) DME Info MIC = 6.3 ug/ml [1]
Cytidine deaminase (cdd) DME Info MIC = 6.3 ug/ml [1]
Cytidine deaminase (cdd) DME Info MIC = 6.3 ug/ml [1]
Chloramphenicolase (chlR) DME Info MIC = 12.5 ug/ml [1]
Glycoside hydrolase (cscA) DME Info MIC = 12.5 ug/ml [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 12.5 ug/ml [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 12.5 ug/ml [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 6.3 ug/ml [1]
Glutamate decarboxylase (gadB) DME Info MIC = 12.5 ug/ml [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 12.5 ug/ml [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 25 ug/ml [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 6.3 ug/ml [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 12.5 ug/ml [1]
Methylthioribose kinase (mtnK) DME Info MIC = 6.3 ug/ml [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 6.3 ug/ml [1]
Glutamate racemase (MurI) DME Info MIC = 12.5 ug/ml [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 25 ug/ml [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 12.5 ug/ml [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 6.3 ug/ml [1]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 6.3 ug/ml [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 12.5 ug/ml [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 12.5 ug/ml [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 6.3 ug/ml [1]
NADH dehydrogenase (nuoE) DME Info MIC = 12.5 ug/ml [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 25 ug/ml [1]
Glutamate racemase (MurI) DME Info MIC = 6.3 ug/ml [1]
Tyramine oxidase (tynA) DME Info MIC = 12.5 ug/ml [1]
Beta-glucuronidase (uidA) DME Info MIC = 12.5 ug/ml [1]
Glutamate racemase (MurI) DME Info MIC = 6.3 ug/ml [1]
General stress protein 14 (ywrO) DME Info MIC = 6.3 ug/ml [1]
References
1 De novo generation of antimicrobial LK peptides with a single tryptophan at the critical amphipathic interface. J Pept Sci. 2009 Sep;15(9):583-8.

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