Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03593)
Xenobiotics Name
Human beta-defensin hBD-3
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella variicola [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1], [2]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1], [2]
Cytidine deaminase (cdd) DME Info Escherichia coli [1], [2]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1], [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 9.4 ug/ml [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 9.4 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 25 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 9.4 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 25 ug/ml [1], [2]
Metallo-beta-lactamase (blaM) DME Info MIC = 25 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 25 ug/ml [1], [2]
Cytidine deaminase (cdd) DME Info MIC = 25 ug/ml [1], [2]
Cytidine deaminase (cdd) DME Info MIC = 25 ug/ml [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 9.4 ug/ml [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 9.4 ug/ml [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 9.4 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 9.4 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 25 ug/ml [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 9.4 ug/ml [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 9.4 ug/ml [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 18.75 ug/ml [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 25 ug/ml [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 9.4 ug/ml [1], [2]
Methylthioribose kinase (mtnK) DME Info MIC = 25 ug/ml [1], [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 25 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 9.4 ug/ml [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 18.75 ug/ml [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 9.4 ug/ml [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 4.7 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 9.4 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 9.4 ug/ml [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 25 ug/ml [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 9.4 ug/ml [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 18.75 ug/ml [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 9.4 ug/ml [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 9.4 ug/ml [1], [2]
References
1 Engineering disulfide bonds of the novel human beta-defensins hBD-27 and hBD-28: differences in disulfide formation and biological activity among human beta-defensins. Biopolymers. 2005;80(1):34-49.
2 Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic. J Biol Chem. 2001 Feb 23;276(8):5707-13.

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