Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO04606)
Xenobiotics Name
Pilosulin Myr b I
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Beta-lactamase (blaB) DME Info Citrobacter freundii [1]
Azoreductase (azoR) DME Info Escherichia coli [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [2]
Beta-lactamase (blaB) DME Info Klebsiella variicola [3]
Beta-lactamase (blaB) DME Info Escherichia coli [2]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [4]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [3]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [3]
Cytidine deaminase (cdd) DME Info Escherichia coli [2]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [3]
Chloramphenicolase (chlR) DME Info Escherichia coli [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [2]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [3]
Unclear metabolic mechanism (DME-unclear) DME Info Citrobacter freundii [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [2]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [3]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [2]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [3]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [3]
Glutamate racemase (MurI) DME Info Escherichia coli [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [2]
Arylamine N-acetyltransferase (NAT) DME Info Citrobacter freundii [1]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [3]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Beta-lactamase (blaB) DME Info MIC = 2 microM [1]
Azoreductase (azoR) DME Info MIC = 2 microM [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 2 microM [2]
Beta-lactamase (blaB) DME Info MIC = 2 microM [3]
Beta-lactamase (blaB) DME Info MIC = 2 microM [2]
Beta-lactamase (blaB) DME Info MIC = 2 microM [4]
Metallo-beta-lactamase (blaM) DME Info MIC = 2 microM [3]
Beta-lactamase (blaB) DME Info MIC = 2 microM [3]
Cytidine deaminase (cdd) DME Info MIC = 2 microM [2]
Cytidine deaminase (cdd) DME Info MIC = 2 microM [3]
Chloramphenicolase (chlR) DME Info MIC = 2 microM [2]
Glycoside hydrolase (cscA) DME Info MIC = 2 microM [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 2 microM [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 2 microM [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 2 microM [3]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 2 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 2 microM [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 2 microM [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 4 microM [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 2 microM [3]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 2 microM [2]
Methylthioribose kinase (mtnK) DME Info MIC = 2 microM [3]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 2 microM [3]
Glutamate racemase (MurI) DME Info MIC = 2 microM [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 4 microM [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 2 microM [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 2 microM [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 2 microM [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 2 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 2 microM [3]
NADH dehydrogenase (nuoE) DME Info MIC = 2 microM [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 4 microM [2]
Tyramine oxidase (tynA) DME Info MIC = 2 microM [2]
Beta-glucuronidase (uidA) DME Info MIC = 2 microM [2]
References
1 Cytotoxicity of pilosulin 1, a peptide from the venom of the jumper ant Myrmecia pilosula. Biochim Biophys Acta. 1998 Sep 16;1425(1):74-80.
2 Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin. Arch Biochem Biophys. 2005 Feb 15;434(2):358-64.
3 Flow cytometric analysis of cell killing by the jumper ant venom peptide pilosulin 1. Cytometry. 1998 Aug 1;32(4):268-73.
4 Expression of jumper ant (Myrmecia pilosula) venom allergens: post-translational processing of allergen gene products. Biochem Mol Biol Int. 1996 Aug;39(5):877-85.

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