Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO05163)
Xenobiotics Name	Tracheal antimicrobial peptide
Xenobiotics Type	Amino Acid(s), Peptide(s) or Protein(s)
Classification	Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
	Azoreductase (azoR)	DME Info	Escherichia coli	[1], [2]
	L,D-carboxypeptidase A (ldcA)	DME Info	Escherichia coli	[1], [2]
	Beta-lactamase (blaB)	DME Info	Klebsiella variicola	[1], [2]
	Beta-lactamase (blaB)	DME Info	Escherichia coli	[1], [2]
	Beta-lactamase (blaB)	DME Info	Klebsiella aerogenes	[1], [2]
	Metallo-beta-lactamase (blaM)	DME Info	Klebsiella pneumoniae	[1], [2]
	Beta-lactamase (blaB)	DME Info	Klebsiella pneumoniae	[1], [2]
	Cytidine deaminase (cdd)	DME Info	Escherichia coli	[1], [2]
	Cytidine deaminase (cdd)	DME Info	Klebsiella pneumoniae	[1], [2]
	Chloramphenicolase (chlR)	DME Info	Escherichia coli	[1], [2]
	Glycoside hydrolase (cscA)	DME Info	Escherichia coli	[1], [2]
	NADPH-dependent curcumin reductase (curA)	DME Info	Escherichia coli	[1], [2]
	Unclear metabolic mechanism (DME-unclear)	DME Info	Escherichia coli	[1], [2]
	Unclear metabolic mechanism (DME-unclear)	DME Info	Klebsiella pneumoniae	[1], [2]
	Glutamate decarboxylase (gadB)	DME Info	Escherichia coli	[1], [2]
	D-Lactate dehydrogenase (ldhA)	DME Info	Escherichia coli	[1], [2]
	D-Lactate dehydrogenase (ldhA)	DME Info	Pseudomonas aeruginosa	[1], [2]
	Molybdopterin-dependent enzyme (molD)	DME Info	Klebsiella pneumoniae	[1], [2]
	Molybdopterin-dependent enzyme (molD)	DME Info	Escherichia coli	[1], [2]
	Methylthioribose kinase (mtnK)	DME Info	Klebsiella pneumoniae	[1], [2]
	S-adenosylhomocysteine nucleosidase (mtnN)	DME Info	Klebsiella pneumoniae	[1], [2]
	Glutamate racemase (MurI)	DME Info	Escherichia coli	[1], [2]
	Arylamine N-acetyltransferase (NAT)	DME Info	Pseudomonas aeruginosa	[1], [2]
	N-ethylmaleimide reductase (nemA)	DME Info	Escherichia coli	[1], [2]
	NADPH-dependent oxidoreductase (nfrA)	DME Info	Staphylococcus aureus	[1], [2]
	Oxygen-insensitive NADPH nitroreductase A (nfsA)	DME Info	Escherichia coli	[1], [2]
	Oxygen-insensitive NADPH nitroreductase B (nfsB)	DME Info	Escherichia coli	[1], [2]
	Arylamine N-acetyltransferase (NAT)	DME Info	Klebsiella pneumoniae	[1], [2]
	NADH dehydrogenase (nuoE)	DME Info	Streptomyces griseus	[1], [2]
	Hydroxybenzoate 3-monooxygenase (pobA)	DME Info	Pseudomonas aeruginosa	[1], [2]
	Tyramine oxidase (tynA)	DME Info	Escherichia coli	[1], [2]
	Beta-glucuronidase (uidA)	DME Info	Escherichia coli	[1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data	Azoreductase (azoR)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	L,D-carboxypeptidase A (ldcA)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Beta-lactamase (blaB)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Beta-lactamase (blaB)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Beta-lactamase (blaB)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Metallo-beta-lactamase (blaM)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Beta-lactamase (blaB)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Cytidine deaminase (cdd)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Cytidine deaminase (cdd)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Chloramphenicolase (chlR)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Glycoside hydrolase (cscA)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	NADPH-dependent curcumin reductase (curA)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Unclear metabolic mechanism (DME-unclear)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Unclear metabolic mechanism (DME-unclear)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Glutamate decarboxylase (gadB)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	D-Lactate dehydrogenase (ldhA)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	D-Lactate dehydrogenase (ldhA)	DME Info	MIC = 25-50 ug/ml	[1], [2]
	Molybdopterin-dependent enzyme (molD)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Molybdopterin-dependent enzyme (molD)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Methylthioribose kinase (mtnK)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	S-adenosylhomocysteine nucleosidase (mtnN)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Glutamate racemase (MurI)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Arylamine N-acetyltransferase (NAT)	DME Info	MIC = 25-50 ug/ml	[1], [2]
	N-ethylmaleimide reductase (nemA)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	NADPH-dependent oxidoreductase (nfrA)	DME Info	MIC = 25-50 ug/ml	[1], [2]
	Oxygen-insensitive NADPH nitroreductase A (nfsA)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Oxygen-insensitive NADPH nitroreductase B (nfsB)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Arylamine N-acetyltransferase (NAT)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	NADH dehydrogenase (nuoE)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Hydroxybenzoate 3-monooxygenase (pobA)	DME Info	MIC = 25-50 ug/ml	[1], [2]
	Tyramine oxidase (tynA)	DME Info	MIC = 12-25 ug/ml	[1], [2]
	Beta-glucuronidase (uidA)	DME Info	MIC = 12-25 ug/ml	[1], [2]

References
1	Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3952-6.
2	Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene. Proc Natl Acad Sci U S A. 1993 May 15;90(10):4596-600.

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