General Information of Xenobiotics (ID: XEO03697)
Xenobiotics Name
Kassinatuerin-1
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
Azoreductase (azoR) DME Info Enterococcus faecalis [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella variicola [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1], [2]
Beta-lactamase (blaB) DME Info Enterobacter cloacae [1], [2]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1], [2]
Cytidine deaminase (cdd) DME Info Escherichia coli [1], [2]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Enterococcus faecalis [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
Beta-galactosidase (bgaB) DME Info Enterobacter cloacae [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1], [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Nitroreductase (NTR) DME Info Enterobacter cloacae [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Retro-nitroreductase (rNR) DME Info Enterobacter cloacae [1], [2]
Tyrosine decarboxylase (tdc) DME Info Enterococcus faecalis [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
VanA ligase (vanA) DME Info Enterococcus faecalis [1], [2]
VanB ligase (vanB) DME Info Enterococcus faecalis [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 6.25 microM [1], [2]
Azoreductase (azoR) DME Info MIC = 12.5 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 6.25 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 25 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 6.25 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 25 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 6.25 microM [1], [2]
Metallo-beta-lactamase (blaM) DME Info MIC = 25 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 25 microM [1], [2]
Cytidine deaminase (cdd) DME Info MIC = 25 microM [1], [2]
Cytidine deaminase (cdd) DME Info MIC = 25 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 6.25 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 6.25 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 6.25 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 6.25 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 25 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 12.5 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 6.25 microM [1], [2]
Beta-galactosidase (bgaB) DME Info MIC = 6.25 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 6.25 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 25 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 25 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 6.25 microM [1], [2]
Methylthioribose kinase (mtnK) DME Info MIC = 25 microM [1], [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 25 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 6.25 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 25 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 6.25 microM [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 6.25 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 6.25 microM [1], [2]
Nitroreductase (NTR) DME Info MIC = 6.25 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 6.25 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 25 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 6.25 microM [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 25 microM [1], [2]
Retro-nitroreductase (rNR) DME Info MIC = 6.25 microM [1], [2]
Tyrosine decarboxylase (tdc) DME Info MIC = 12.5 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 6.25 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 6.25 microM [1], [2]
VanA ligase (vanA) DME Info MIC = 12.5 microM [1], [2]
VanB ligase (vanB) DME Info MIC = 12.5 microM [1], [2]
References
1 Kassinatuerin-1: a peptide with broad-spectrum antimicrobial activity isolated from the skin of the hyperoliid frog, Kassina senegalensis. Biochem Biophys Res Commun. 2000 Feb 16;268(2):433-6.
2 Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. Peptides. 2005 Nov;26(11):2104-10.

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