General Information of Xenobiotics (ID: XEO03775)
Xenobiotics Name
Bacteriocin lactocyclicin Q
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Enterococcus faecium [1], [2]
L-arabinose isomerase (araA) DME Info Lactobacillus sakei [1], [2]
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
Azoreductase (azoR) DME Info Streptococcus salivarius [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-glucosidase (bglA) DME Info Enterococcus faecium [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Lactococcus lactis [1], [2]
Dihydrofolate reductase (folA) DME Info Escherichia coli [1], [2]
Dihydrofolate reductase (folA) DME Info Lactobacillus casei [1], [2]
Folylpolyglutamate synthetase (fpgS) DME Info Lactobacillus casei [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
Glutamate decarboxylase (gadB) DME Info Lactococcus lactis [1], [2]
Inositol dehydrogenase (idh) DME Info Lactobacillus casei [1], [2]
Inositol dehydrogenase (idh) DME Info Lactobacillus casei [1], [2]
L-Lactate dehydrogenase (ldh) DME Info Lactobacillus casei [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
Lactate racemase (Lsa784) DME Info Lactobacillus sakei [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Tripeptidase (pepT) DME Info Lactococcus lactis [1], [2]
Dipeptidase (pepV) DME Info Lactococcus lactis [1], [2]
Pyruvate oxidase (pyrO) DME Info Lactobacillus casei [1], [2]
Thymidylate synthase (thyA) DME Info Lactobacillus casei [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Lactobacillus sakei [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
VanA ligase (vanA) DME Info Enterococcus faecium [1], [2]
VanB ligase (vanB) DME Info Enterococcus faecium [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.71 microM [1], [2]
L-arabinose isomerase (araA) DME Info MIC = 0.015 microM [1], [2]
Azoreductase (azoR) DME Info MIC = 17.3 microM [1], [2]
Azoreductase (azoR) DME Info MIC = 22.9 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 17.3 microM [1], [2]
Beta-glucosidase (bglA) DME Info MIC = 0.71 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 17.3 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 17.3 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 17.3 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 17.3 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 17.3 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.141 microM [1], [2]
Dihydrofolate reductase (folA) DME Info MIC = 2.27 microM [1], [2]
Dihydrofolate reductase (folA) DME Info MIC = 2.27 microM [1], [2]
Folylpolyglutamate synthetase (fpgS) DME Info MIC = 2.27 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 17.3 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 0.141 microM [1], [2]
Inositol dehydrogenase (idh) DME Info MIC = 2.27 microM [1], [2]
Inositol dehydrogenase (idh) DME Info MIC = 2.27 microM [1], [2]
L-Lactate dehydrogenase (ldh) DME Info MIC = 2.27 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 17.3 microM [1], [2]
Lactate racemase (Lsa784) DME Info MIC = 0.015 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 17.3 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 17.3 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 17.3 microM [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 91.6 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 17.3 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 17.3 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 17.3 microM [1], [2]
Tripeptidase (pepT) DME Info MIC = 0.141 microM [1], [2]
Dipeptidase (pepV) DME Info MIC = 0.141 microM [1], [2]
Pyruvate oxidase (pyrO) DME Info MIC = 2.27 microM [1], [2]
Thymidylate synthase (thyA) DME Info MIC = 2.27 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 17.3 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 0.015 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 17.3 microM [1], [2]
VanA ligase (vanA) DME Info MIC = 0.71 microM [1], [2]
VanB ligase (vanB) DME Info MIC = 0.71 microM [1], [2]
References
1 Identification and characterization of lactocyclicin Q, a novel cyclic bacteriocin produced by Lactococcus spstrain QU 12. Appl Environ Microbiol. 2009 Mar;75(6):1552-8.
2 Identification and characterization of leucocyclicin Q, a novel cyclic bacteriocin produced by Leuconostoc mesenteroides TK41401. Appl Environ Microbiol. 2011 Nov;77(22):8164-70.

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