Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO03556) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Hagfish HFIAP-1/2
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| Xenobiotics Type |
Amino Acid(s), Peptide(s) or Protein(s)
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| Classification |
Peptide
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| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Aminoglycoside N-acetyltransferase (aacC2) | DME Info | Acinetobacter baumannii | [1] | |||
| Azoreductase (azoR) | DME Info | Enterococcus faecium | [1] | |||
| Flavin adenine dinucleotide dehydrogenase (fadd) | DME Info | Clostridium perfringens | [1] | |||
| Aminoglycoside O-phosphotransferase (aphA6) | DME Info | Acinetobacter baumannii | [1] | |||
| Azoreductase (azoR) | DME Info | Escherichia coli | [1] | |||
| Azoreductase (azoR) | DME Info | Enterococcus faecalis | [1] | |||
| Azoreductase (azoR) | DME Info | Clostridium perfringens | [1] | |||
| Azoreductase (azoR) | DME Info | Streptococcus pyogenes | [1] | |||
| L,D-carboxypeptidase A (ldcA) | DME Info | Escherichia coli | [1] | |||
| Beta-glucosidase (bglA) | DME Info | Enterococcus faecium | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella variicola | [1] | |||
| Beta-lactamase (blaB) | DME Info | Escherichia coli | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella aerogenes | [1] | |||
| Beta-lactamase (blaB) | DME Info | Corynebacterium acnes | [1] | |||
| Beta-lactamase (blaB) | DME Info | Enterobacter cloacae | [1] | |||
| Beta-lactamase (blaB) | DME Info | Acinetobacter baumannii | [1] | |||
| Metallo-beta-lactamase (blaM) | DME Info | Klebsiella pneumoniae | [1] | |||
| Beta-lactamase (blaB) | DME Info | Shigella sonnei | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella pneumoniae | [1] | |||
| Cytidine deaminase (cdd) | DME Info | Escherichia coli | [1] | |||
| Cytidine deaminase (cdd) | DME Info | Klebsiella pneumoniae | [1] | |||
| Chloramphenicolase (chlR) | DME Info | Escherichia coli | [1] | |||
| Glycoside hydrolase (cscA) | DME Info | Escherichia coli | [1] | |||
| NADPH-dependent curcumin reductase (curA) | DME Info | Escherichia coli | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Clostridium perfringens | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Escherichia coli | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Klebsiella pneumoniae | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Enterococcus faecalis | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | Escherichia coli | [1] | |||
| Beta-galactosidase (bgaB) | DME Info | Enterobacter cloacae | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Escherichia coli | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | Klebsiella pneumoniae | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | Escherichia coli | [1] | |||
| Methylthioribose kinase (mtnK) | DME Info | Klebsiella pneumoniae | [1] | |||
| S-adenosylhomocysteine nucleosidase (mtnN) | DME Info | Klebsiella pneumoniae | [1] | |||
| Glutamate racemase (MurI) | DME Info | Escherichia coli | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Pseudomonas aeruginosa | [1] | |||
| N-ethylmaleimide reductase (nemA) | DME Info | Escherichia coli | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | Staphylococcus aureus | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | Escherichia coli | [1] | |||
| Nitroreductase (NTR) | DME Info | Enterobacter cloacae | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | Escherichia coli | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Klebsiella pneumoniae | [1] | |||
| Nitroreductase (NTR) | DME Info | Clostridium perfringens | [1] | |||
| NADH dehydrogenase (nuoE) | DME Info | Streptomyces griseus | [1] | |||
| Nicotinamidase (pncA) | DME Info | Acinetobacter baumannii | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Retro-nitroreductase (rNR) | DME Info | Enterobacter cloacae | [1] | |||
| Tyrosine decarboxylase (tdc) | DME Info | Enterococcus faecalis | [1] | |||
| Tyramine oxidase (tynA) | DME Info | Escherichia coli | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | Clostridium perfringens | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | Escherichia coli | [1] | |||
| VanA ligase (vanA) | DME Info | Enterococcus faecalis | [1] | |||
| VanA ligase (vanA) | DME Info | Enterococcus faecium | [1] | |||
| VanB ligase (vanB) | DME Info | Enterococcus faecium | [1] | |||
| VanB ligase (vanB) | DME Info | Enterococcus faecalis | [1] | |||
| Xenobiotics-DME Activity Data | ||||||
| Xenobiotics-DME Activity Data | Aminoglycoside N-acetyltransferase (aacC2) | DME Info | MIC = 8-16 ug/ml | [1] | ||
| Azoreductase (azoR) | DME Info | MIC = 4-8 ug/ml | [1] | |||
| Flavin adenine dinucleotide dehydrogenase (fadd) | DME Info | MIC = 4-32 ug/ml | [1] | |||
| Aminoglycoside O-phosphotransferase (aphA6) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Azoreductase (azoR) | DME Info | MIC = 8 ug/ml | [1] | |||
| Azoreductase (azoR) | DME Info | MIC = 32 ug/ml | [1] | |||
| Azoreductase (azoR) | DME Info | MIC = 4-32 ug/ml | [1] | |||
| Azoreductase (azoR) | DME Info | MIC = 4 ug/ml | [1] | |||
| L,D-carboxypeptidase A (ldcA) | DME Info | MIC = 8 ug/ml | [1] | |||
| Beta-glucosidase (bglA) | DME Info | MIC = 4-8 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 8 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 2 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Metallo-beta-lactamase (blaM) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 2-4 ug/ml | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Cytidine deaminase (cdd) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Cytidine deaminase (cdd) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Chloramphenicolase (chlR) | DME Info | MIC = 8 ug/ml | [1] | |||
| Glycoside hydrolase (cscA) | DME Info | MIC = 8 ug/ml | [1] | |||
| NADPH-dependent curcumin reductase (curA) | DME Info | MIC = 8 ug/ml | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 4-32 ug/ml | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 8 ug/ml | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 32 ug/ml | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | MIC = 8 ug/ml | [1] | |||
| Beta-galactosidase (bgaB) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC = 8 ug/ml | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC = 8 ug/ml | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | MIC = 8 ug/ml | [1] | |||
| Methylthioribose kinase (mtnK) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| S-adenosylhomocysteine nucleosidase (mtnN) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Glutamate racemase (MurI) | DME Info | MIC = 8 ug/ml | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 8 ug/ml | [1] | |||
| N-ethylmaleimide reductase (nemA) | DME Info | MIC = 8 ug/ml | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | MIC = 8 ug/ml | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | MIC = 8 ug/ml | [1] | |||
| Nitroreductase (NTR) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | MIC = 8 ug/ml | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Nitroreductase (NTR) | DME Info | MIC = 4-32 ug/ml | [1] | |||
| NADH dehydrogenase (nuoE) | DME Info | MIC = 8 ug/ml | [1] | |||
| Nicotinamidase (pncA) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | MIC = 8 ug/ml | [1] | |||
| Retro-nitroreductase (rNR) | DME Info | MIC = 8-16 ug/ml | [1] | |||
| Tyrosine decarboxylase (tdc) | DME Info | MIC = 32 ug/ml | [1] | |||
| Tyramine oxidase (tynA) | DME Info | MIC = 8 ug/ml | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | MIC = 4-32 ug/ml | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | MIC = 8 ug/ml | [1] | |||
| VanA ligase (vanA) | DME Info | MIC = 32 ug/ml | [1] | |||
| VanA ligase (vanA) | DME Info | MIC = 4-8 ug/ml | [1] | |||
| VanB ligase (vanB) | DME Info | MIC = 4-8 ug/ml | [1] | |||
| VanB ligase (vanB) | DME Info | MIC = 32 ug/ml | [1] | |||
| References | ||||||
| 1 | Hagfish intestinal antimicrobial peptides are ancient cathelicidins. Peptides. 2003 Nov;24(11):1655-67. | |||||
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